Human GPR125 (ADGRA3) activation kit by CRISPRa

CAT#: GA116142

ADGRA3 CRISPRa kit - CRISPR gene activation of human adhesion G protein-coupled receptor A3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADGRA3
• Locus ID: 166647
• Kit Components:

  GA116142G1, ADGRA3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116142G2, ADGRA3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116142G3, ADGRA3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_145290
• Synonyms: GPR125; PGR21; TEM5L
• Summary: This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene. This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2012]