Human SPRED2 activation kit by CRISPRa

CAT#: GA116359

SPRED2 CRISPRa kit - CRISPR gene activation of human sprouty related EVH1 domain containing 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SPRED2
• Locus ID: 200734
• Kit Components:

  GA116359G1, SPRED2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116359G2, SPRED2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116359G3, SPRED2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001128210, NM_181784
• Synonyms: Spred-2
• Summary: SPRED2 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]). [supplied by OMIM, Mar 2008]