Human ARL13B activation kit by CRISPRa

CAT#: GA116365

ARL13B CRISPRa kit - CRISPR gene activation of human ADP ribosylation factor like GTPase 13B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARL13B
• Locus ID: 200894
• Kit Components:

  GA116365G1, ARL13B gRNA vector 1 in pCas-Guide-CRISPRa

  GA116365G2, ARL13B gRNA vector 2 in pCas-Guide-CRISPRa

  GA116365G3, ARL13B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001174150, NM_001174151, NM_144996, NM_182896, NR_033427, NM_001321328, NR_135621
• Synonyms: ARL2L1; JBTS8
• Summary: This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]