Human GPR115 (ADGRF4) activation kit by CRISPRa

CAT#: GA116612

ADGRF4 CRISPRa kit - CRISPR gene activation of human adhesion G protein-coupled receptor F4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADGRF4
• Locus ID: 221393
• Kit Components:

  GA116612G1, ADGRF4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116612G2, ADGRF4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116612G3, ADGRF4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_153838, NM_001347855
• Synonyms: GPR115; PGR18
• Summary: Sequence analysis of this gene suggests that it is encodes a member of the superfamily of G protein-couple receptors. G protein-coupled receptors typically contain seven hydrophobic transmembrane domains, interact with guanine nucleotide binding regulatory proteins, and detect molecules outside the cell and act to transduce these signals into intracellular responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]