Human MDGA1 activation kit by CRISPRa

CAT#: GA116947

MDGA1 CRISPRa kit - CRISPR gene activation of human MAM domain containing glycosylphosphatidylinositol anchor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MDGA1
• Locus ID: 266727
• Kit Components:

  GA116947G1, MDGA1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116947G2, MDGA1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116947G3, MDGA1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_153487
• Synonyms: GPIM; MAMDC3
• Summary: This gene encodes a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that is expressed predominantly in the developing nervous system. In addition to possessing several cell adhesion molecule-like domains, the mature protein has six Ig-like domains, a single fibronectin type III domain, a MAM domain and a C-terminal GPI-anchoring site. Studies in other mammals suggest this protein plays a role in cell adhesion, migration, and axon guidance and, in the developing brain, neuronal migration. In humans, this gene is associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2016]