Human BOLA3 activation kit by CRISPRa

CAT#: GA118012

BOLA3 CRISPRa kit - CRISPR gene activation of human bolA family member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BOLA3
• Locus ID: 388962
• Kit Components:

  GA118012G1, BOLA3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA118012G2, BOLA3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA118012G3, BOLA3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001035505, NM_212552
• Synonyms: MMDS2
• Summary: This gene encodes a protein that plays an essential role in the production of iron-sulfur (Fe-S) clusters for the normal maturation of lipoate-containing 2-oxoacid dehydrogenases, and for the assembly of the mitochondrial respiratory chain complexes. Mutation in this gene has been associated with multiple mitochondrial dysfunctions syndrome-2. Two alternatively spliced transcript variants encoding different isoforms with distinct subcellular localization have been reported for this gene (PMID:21944046). [provided by RefSeq, Dec 2011]