Mouse Adam19 activation kit by CRISPRa

CAT#: GA200064

Adam19 CRISPRa kit - CRISPR gene activation of mouse a disintegrin and metallopeptidase domain 19 (meltrin beta)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Adam19
• Locus ID: 11492
• Kit Components:

  GA200064G1, Adam19 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200064G2, Adam19 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200064G3, Adam19 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001291890, NM_001291891, NM_001311209, NM_009616
• Synonyms: AL024287; MADDAM; Mltnb; MTLNB
• Summary: This gene encodes a cell surface glycoprotein and member of the ADAM (a disintegrin and metalloproteinase) family of endopeptidases. The encoded protein may play a role in the ectodomain shedding of neuregulin proteins. Homozygous knockout mice for this gene exhibit heart development defects and perinatal lethality. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that undergoes proteolytic processing to generate a mature protein product. [provided by RefSeq, Aug 2015]