Mouse Ank3 activation kit by CRISPRa

CAT#: GA200187

Ank3 CRISPRa kit - CRISPR gene activation of mouse ankyrin 3, epithelial

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ank3
• Locus ID: 11735
• Kit Components:

  GA200187G1, Ank3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200187G2, Ank3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200187G3, Ank3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009670, NM_146005, NM_170687, NM_170688, NM_170689, NM_170690, NM_170728, NM_170729, NM_170730
• Synonyms: 2900054D09Rik; AI314020; Ank-3; AnkG; Ankyrin-3; Ankyrin-G
• Summary: This gene encodes a member of the ankyrin protein family. Ankyrins link integral membrane proteins to the spectrin-based cytoskeleton. Ankyrin family members share a protein structure which includes three independently folded domains: the N-terminal ankyrin repeat domain, the central spectrin-binding domain, and the C-terminal rod domain. This ankyrin functions as the major ankyrin in the kidney and may play a role in the polarized distribution of many integral membrane proteins to specific subcellular sites. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]