Mouse Rhoa activation kit by CRISPRa

CAT#: GA200272

Rhoa CRISPRa kit - CRISPR gene activation of mouse ras homolog family member A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Rhoa
• Locus ID: 11848
• Kit Components:

  GA200272G1, Rhoa gRNA vector 1 in pCas-Guide-CRISPRa

  GA200272G2, Rhoa gRNA vector 2 in pCas-Guide-CRISPRa

  GA200272G3, Rhoa gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001313961, NM_001313962, NM_016802
• Synonyms: Arha; Arha1; Arha2
• Summary: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]