Mouse Casp9 activation kit by CRISPRa

CAT#: GA200542

Casp9 CRISPRa kit - CRISPR gene activation of mouse caspase 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Casp9
• Locus ID: 12371
• Kit Components:

  GA200542G1, Casp9 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200542G2, Casp9 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200542G3, Casp9 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001277932, NM_015733, NM_001355176
• Synonyms: AI115399; APAF-3; AW493809; CASP-9; Caspase-9; ICE-LAP6; Mch6
• Summary: This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, the initiator caspase, is activated after cytochrome c release from mitochondria and targets downstream effectors. In mouse, deficiency of this gene can cause perinatal lethality. This protein may have a role in normal brain development. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013]