Mouse Vsx2 activation kit by CRISPRa

CAT#: GA200728

Vsx2 CRISPRa kit - CRISPR gene activation of mouse visual system homeobox 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Vsx2
• Locus ID: 12677
• Kit Components:

  GA200728G1, Vsx2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200728G2, Vsx2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200728G3, Vsx2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301427, NM_007701
• Synonyms: Chx10; Hox-10; Hox10; or
• Summary: This gene encodes a member of the Vsx (visual system homeobox) family which belongs to the larger PRD homeobox class. The encoded protein is required for eye organogenesis and controls retinal development. Disruption of this gene is associated with ocular retardation J (orJ), a mouse disease which causes microphthalmia, retinal degeneration and optic nerve aplasia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]