Mouse Dsc2 activation kit by CRISPRa

CAT#: GA201135

Dsc2 CRISPRa kit - CRISPR gene activation of mouse desmocollin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Dsc2
• Locus ID: 13506
• Kit Components:

  GA201135G1, Dsc2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201135G2, Dsc2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201135G3, Dsc2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001317363, NM_001317365, NM_013505
• Synonyms: AW228162
• Summary: This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]