Mouse Folr2 activation kit by CRISPRa

CAT#: GA201462

Folr2 CRISPRa kit - CRISPR gene activation of mouse folate receptor 2 (fetal)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Folr2
• Locus ID: 14276
• Kit Components:

  GA201462G1, Folr2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201462G2, Folr2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201462G3, Folr2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001303231, NM_001303239, NM_008035
• Synonyms: FBP2; Folbp-2; Folbp2; FR-beta; FR-P3
• Summary: This gene encodes a receptor protein located on the plasma membrane that mediates folate uptake by cells. Mice lacking the product of this gene show no defects in embryonic development and grow normally into fertile adults. However, such mice were found to be highly susceptible to the teratogenic effects of arsenic. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]