Mouse Ghrh activation kit by CRISPRa

CAT#: GA201606

Ghrh CRISPRa kit - CRISPR gene activation of mouse growth hormone releasing hormone

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ghrh
• Locus ID: 14601
• Kit Components:

  GA201606G1, Ghrh gRNA vector 1 in pCas-Guide-CRISPRa

  GA201606G2, Ghrh gRNA vector 2 in pCas-Guide-CRISPRa

  GA201606G3, Ghrh gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001329683, NM_010285
• Synonyms: Ghrf; GRF
• Summary: This gene encodes a hormone that has stimulatory effects on pituitary growth hormone synthesis and release, and somatotrope expansion. The encoded preproprotein undergoes proteolytic processing to generate the mature peptide that is secreted by hypothalamus. Mice lacking the encoded protein are deficient in the growth hormone, live longer and exhibit growth retardation, enhanced insulin sensitivity and increased xenobiotic metabolism. [provided by RefSeq, Jul 2016]