Mouse Itgb7 activation kit by CRISPRa

CAT#: GA202210

Itgb7 CRISPRa kit - CRISPR gene activation of mouse integrin beta 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Itgb7
• Locus ID: 16421
• Kit Components:

  GA202210G1, Itgb7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202210G2, Itgb7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202210G3, Itgb7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_013566
• Synonyms: Ly69
• Summary: Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is involved in adhesive interactions of leukocytes. It is a receptor for fibronectin and recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Integrin alpha-4/beta-7 is also a receptor for MADCAM1 and VCAM1. It recognizes the sequence L-D-T in MADCAM1. Integrin alpha-E/beta-7 is a receptor for E-cadherin. [UniProtKB/Swiss-Prot Function]