Mouse Hip1r activation kit by CRISPRa

CAT#: GA205231

Hip1r CRISPRa kit - CRISPR gene activation of mouse huntingtin interacting protein 1 related

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Hip1r
• Locus ID: 29816
• Kit Components:

  GA205231G1, Hip1r gRNA vector 1 in pCas-Guide-CRISPRa

  GA205231G2, Hip1r gRNA vector 2 in pCas-Guide-CRISPRa

  GA205231G3, Hip1r gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_145070
• Synonyms: AA410023; mKIAA0655
• Summary: Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. [UniProtKB/Swiss-Prot Function]