Mouse Angptl3 activation kit by CRISPRa

CAT#: GA205280

Angptl3 CRISPRa kit - CRISPR gene activation of mouse angiopoietin-like 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Angptl3
• Locus ID: 30924
• Kit Components:

  GA205280G1, Angptl3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA205280G2, Angptl3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA205280G3, Angptl3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_013913
• Synonyms: hypl
• Summary: This gene encodes a member of the angiopoietin-like family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may inhibit triglyceride metabolism. Homozygous knockout mice for this gene exhibit reduced plasma lipid concentrations, including reduced plasma triglyceride concentrations, and enhanced activity of enzymes involved in triglyceride metabolism. [provided by RefSeq, Aug 2015]