Mouse Osbp2 activation kit by CRISPRa
CAT#: GA209823
Osbp2 CRISPRa kit - CRISPR gene activation of mouse oxysterol binding protein 2
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | Osbp2 |
Locus ID | 74309 |
Kit Components | GA209823G1, Osbp2 gRNA vector 1 in pCas-Guide-CRISPRa GA209823G2, Osbp2 gRNA vector 2 in pCas-Guide-CRISPRa GA209823G3, Osbp2 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001302630, NM_001302631, NM_152818, NM_001363163, NM_001363164 |
Synonyms | 1700095P05Rik; C630001G20Rik; Gm244; ORP-4; OSBPL1 |
Summary | The protein encoded by this gene belongs to the oxysterol-binding protein-related family of proteins, which are defined by a C-terminal sterol domain with a highly conserved EQVSHHPP motif. Oxysterols are oxygenated derivatives of cholesterol that are involved in mechanisms that include apoptosis, cholesterol homeostasis, lipid trafficking and cell differentiation. This protein is selectively expressed at high levels in the brain and testis. Within the testis, the mRNA is localized to postmeiotic germ cells, including spermatids and spermatozoa, but is not detectable in somatic cells. Mice homozygous mutant for a targeted deletion in this gene do not exhibit overt developmental phenotypes but are male sterile. Females display normal fertility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN512638 | Osbp2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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