Mouse Ano10 activation kit by CRISPRa

CAT#: GA211708

Ano10 CRISPRa kit - CRISPR gene activation of mouse anoctamin 10

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ano10
• Locus ID: 102566
• Kit Components:

  GA211708G1, Ano10 gRNA vector 1 in pCas-Guide-CRISPRa

  GA211708G2, Ano10 gRNA vector 2 in pCas-Guide-CRISPRa

  GA211708G3, Ano10 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271873, NM_133979
• Synonyms: AI604832; Tmem16k
• Summary: This gene encodes a member of the anoctamin family, which in mammals is comprised of 10 members. Anoctamin proteins are proposed to have eight transmembrane domains with both termini facing the cytoplasm and a C-terminal domain of unknown function. While some members have been characterized as calcium-activated chloride channels, this protein is reported to inhibit anion conductance. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Dec 2012]