Mouse Klf16 activation kit by CRISPRa

CAT#: GA212491

Klf16 CRISPRa kit - CRISPR gene activation of mouse Kruppel-like factor 16

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Klf16
• Locus ID: 118445
• Kit Components:

  GA212491G1, Klf16 gRNA vector 1 in pCas-Guide-CRISPRa

  GA212491G2, Klf16 gRNA vector 2 in pCas-Guide-CRISPRa

  GA212491G3, Klf16 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_078477
• Synonyms: AI843742; BTEB4; DRRF
• Summary: Transcription factor that binds GC and GT boxes in the D1A, D2 and D3 dopamine receptor promoters and displaces Sp1 and Sp3 from these sequences. It modulates dopaminergic transmission in the brain by repressing or activating transcription from several different promoters depending on cellular context. [UniProtKB/Swiss-Prot Function]