Mouse E2f2 activation kit by CRISPRa

CAT#: GA215074

E2f2 CRISPRa kit - CRISPR gene activation of mouse E2F transcription factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: E2f2
• Locus ID: 242705
• Kit Components:

  GA215074G1, E2f2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA215074G2, E2f2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA215074G3, E2f2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001305399, NM_177733, NM_183301
• Synonyms: E2F-2
• Summary: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner. [UniProtKB/Swiss-Prot Function]