PRPK (TP53RK) Human Gene Knockout Kit (CRISPR)
CAT#: KN209748BN
TP53RK - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | TP53RK |
Locus ID | 112858 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_033550 |
Synonyms | BUD32; C20orf64; dJ101A2; Nori-2; Nori-2p; PRPK |
Summary | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP (By similarity). Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation. [UniProtKB/Swiss-Prot Function] |
Documents
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN209748 | TP53RK - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN209748LP | TP53RK - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN209748RB | TP53RK - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN409748 | TP53RK - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA114374 | TP53RK CRISPRa kit - CRISPR gene activation of human TP53 regulating kinase |
USD 1,290.00 |
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