PERK (EIF2AK3) Human Gene Knockout Kit (CRISPR)
CAT#: KN214993
EIF2AK3 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | GFP-puro |
Symbol | EIF2AK3 |
Locus ID | 9451 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001313915, NM_004836 |
Synonyms | PEK; PERK; WRS |
Summary | The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015] |
Documents
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FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN214993BN | EIF2AK3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN214993LP | EIF2AK3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN214993RB | EIF2AK3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN414993 | EIF2AK3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA106311 | EIF2AK3 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 2 alpha kinase 3 |
USD 1,290.00 |
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