Nectin 3 (NECTIN3) Human Gene Knockout Kit (CRISPR)
CAT#: KN222962LP
PVRL3 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | NECTIN3 |
Locus ID | 25945 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001243286, NM_001243288, NM_015480 |
Synonyms | CD113; CDW113; NECTIN-3; PPR3; PRR3; PVRR3 |
Summary | This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] |
Documents
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FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN222962 | NECTIN3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN222962BN | PVRL3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN222962RB | PVRL3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN422962 | PVRL3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA108650 | NECTIN3 CRISPRa kit - CRISPR gene activation of human nectin cell adhesion molecule 3 |
USD 1,290.00 |
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