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POLE Human Gene Knockout Kit (CRISPR)
CAT#: KN224742LP
POLE - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
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Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
| Donor DNA | Luciferase-Puro |
| Symbol | POLE |
| Locus ID | 5426 |
| Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_006231 |
| Synonyms | CRCS12; FILS; POLE1 |
| Summary | 'This gene encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in this gene have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature. [provided by RefSeq, Sep 2013]' |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| KN224742 | POLE - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
| KN224742BN | POLE - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
| KN224742RB | POLE - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
| KN424742 | POLE - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
| GA103649 | POLE CRISPRa kit - CRISPR gene activation of human DNA polymerase epsilon, catalytic subunit |
USD 1,290.00 |
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