DC2L1 (DYNC2LI1) Human Gene Knockout Kit (CRISPR)
CAT#: KN402656
DYNC2LI1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN402656 is the updated version of KN202656.
USD 1,290.00
2 Weeks*
Size
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Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | DYNC2LI1 |
Locus ID | 51626 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001012665, NM_001193464, NM_015522, NM_016008, NM_001348912, NM_001348913 |
Synonyms | CGI-60; D2LIC; DKFZp564A033; dynein, cytoplasmic 2, light intermediate chain 1; dynein 2 light intermediate chain; LIC3 |
Summary | This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA109908 | DYNC2LI1 CRISPRa kit - CRISPR gene activation of human dynein cytoplasmic 2 light intermediate chain 1 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.