ZNF331 Human Gene Knockout Kit (CRISPR)

CAT#: KN403561

ZNF331 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: ZNF331
• Locus ID: 55422
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001079906, NM_001079907, NM_001253798, NM_001253799, NM_001253800, NM_001253801, NM_001317113, NM_001317114, NM_001317115, NM_001317116, NM_001317117, NM_001317118, NM_001317119, NM_001317120, NM_001317121, NM_018555
• Synonyms: RITA; ZNF361; ZNF463
• Summary: This gene encodes a zinc finger protein containing a KRAB (Kruppel-associated box) domain found in transcriptional repressors. This gene may be methylated and silenced in cancer cells. This gene is located within a differentially methylated region (DMR) and shows allele-specific expression in placenta. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding the same protein. [provided by RefSeq, Nov 2015]