ERp57 (PDIA3) Human Gene Knockout Kit (CRISPR)
CAT#: KN405940
PDIA3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | ERp57 |
Locus ID | 2923 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_005313 |
Synonyms | ER60; ERp57; ERp60; ERp61; GRP57; GRP58; HEL-S-93n; HEL-S-269; HsT17083; P58; PI-PLC |
Summary | 'This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates. [provided by RefSeq, Dec 2016]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN205940 | PDIA3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN205940BN | PDIA3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN205940LP | PDIA3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN205940RB | PDIA3 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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GA101978 | PDIA3 CRISPRa kit - CRISPR gene activation of human protein disulfide isomerase family A member 3 |
USD 1,290.00 |
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