SGEF (ARHGEF26) Human Gene Knockout Kit (CRISPR)

CAT#: KN409727

ARHGEF26 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN409727 is the updated version of KN209727.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol ARHGEF26
Locus ID 26084
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001251962, NM_001251963, NM_015595
Synonyms CSGEF; HMFN1864; SGEF
Summary This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Other Versions

SKU Description Size Price
GA108740 ARHGEF26 CRISPRa kit - CRISPR gene activation of human Rho guanine nucleotide exchange factor 26
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.