p53R2 (RRM2B) Human Gene Knockout Kit (CRISPR)
CAT#: KN410340
RRM2B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN410340 is the updated version of KN210340.
USD 1,290.00
2 Weeks*
Size
Other products for "RRM2B"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | RRM2B |
Locus ID | 50484 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001172477, NM_001172478, NM_015713 |
Synonyms | MTDPS8A; MTDPS8B; P53R2 |
Summary | This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010] |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA109413 | RRM2B CRISPRa kit - CRISPR gene activation of human ribonucleotide reductase regulatory TP53 inducible subunit M2B |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.