KALRN Human Gene Knockout Kit (CRISPR)

CAT#: KN412445

KALRN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.



KN2.0 knockout kit validation

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KN412445 is the updated version of KN212445.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol KALRN
Locus ID 8997
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001024660, NM_003947, NM_007064, NR_028136, NM_001322988, NM_001322989, NM_001322990, NM_001322991, NM_001322992, NM_001322993, NM_001322994, NM_001322995, NM_001322996, NM_001322997, NM_001322998, NM_001322999, NM_001323000, NM_001323001
Synonyms ARHGEF24; CHD5; CHDS5; DUET; DUO; HAPIP; TRAD
Summary Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.