NCoR (NCOR1) Human Gene Knockout Kit (CRISPR)
CAT#: KN413467
NCOR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | NCOR1 |
Locus ID | 9611 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001190438, NM_001190440, NM_006311 |
Synonyms | hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1 |
Summary | This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20. [provided by RefSeq, Jun 2010] |
Documents
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FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
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KN213467 | NCOR1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN213467BN | NCOR1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN213467LP | NCOR1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN213467RB | NCOR1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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GA106435 | NCOR1 CRISPRa kit - CRISPR gene activation of human nuclear receptor corepressor 1 |
USD 1,290.00 |
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