CELF2 Human Gene Knockout Kit (CRISPR)

CAT#: KN416854

CELF2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: CELF2
• Locus ID: 10659
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001025076, NM_001025077, NM_001083591, NM_006561, NM_001326317, NM_001326318, NM_001326319, NM_001326320, NM_001326321, NM_001326323, NM_001326324, NM_001326325, NM_001326326, NM_001326327, NM_001326328, NM_001326329, NM_001326330, NM_001326331, NM_001326332, NM_001326333, NM_001326334, NM_001326335, NM_001326336, NM_001326337, NM_001326338, NM_001326339, NM_001326340, NM_001326341, NM_001326342, NM_001326343, NM_001326344, NM_001326345, NM_001326346, NM_001326347, NM_001326348, NM_001326349
• Synonyms: BRUNOL3; CUGBP2; ETR-3; ETR3; NAPOR
• Summary: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]