ARHGAP8 Human Gene Knockout Kit (CRISPR)
CAT#: KN418707
ARHGAP8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN418707 is the updated version of KN218707.
USD 1,290.00
2 Weeks*
Size
Other products for "ARHGAP8"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | ARHGAP8 |
Locus ID | 23779 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001017526, NM_001198726, NM_017701, NM_181335 |
Synonyms | BPGAP1; PP610 |
Summary | This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq, Nov 2010] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA108500 | ARHGAP8 CRISPRa kit - CRISPR gene activation of human Rho GTPase activating protein 8 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.