Osbp2 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN512638
Osbp2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN512638 is the updated version of KN312638.
USD 1,290.00
2 Weeks*
Size
Other products for "Osbp2"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | Osbp2 |
Locus ID | 74309 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001302630, NM_001302631, NM_152818, NM_001363163, NM_001363164 |
Synonyms | 1700095P05Rik; C630001G20Rik; Gm244; ORP-4; OSBPL1 |
Summary | The protein encoded by this gene belongs to the oxysterol-binding protein-related family of proteins, which are defined by a C-terminal sterol domain with a highly conserved EQVSHHPP motif. Oxysterols are oxygenated derivatives of cholesterol that are involved in mechanisms that include apoptosis, cholesterol homeostasis, lipid trafficking and cell differentiation. This protein is selectively expressed at high levels in the brain and testis. Within the testis, the mRNA is localized to postmeiotic germ cells, including spermatids and spermatozoa, but is not detectable in somatic cells. Mice homozygous mutant for a targeted deletion in this gene do not exhibit overt developmental phenotypes but are male sterile. Females display normal fertility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA209823 | Osbp2 CRISPRa kit - CRISPR gene activation of mouse oxysterol binding protein 2 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.