GUCY1B1 (NM_000857) Human Mass Spec Standard
CAT#: PH308205
GUCY1B3 MS Standard C13 and N15-labeled recombinant protein (NP_000848)
Specifications
Product Data | |
Tag | C-Myc/DDK |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC208205 |
Predicted MW | 70.5 kDa |
Protein Sequence |
>RC208205 protein sequence
Red=Cloning site Green=Tags(s) MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMF GKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSERE GLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISP YTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRS KEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATR DLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNV TILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCI HHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKG KINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETKQDDD TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | 50 ug/ml as determined by BCA |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_000848 |
RefSeq Size | 3261 |
RefSeq ORF | 1857 |
Synonyms | GC-S-beta-1; GC-SB3; GUC1B3; GUCB3; GUCSB3; GUCY1B3 |
Locus ID | 2983 |
UniProt ID | Q02153 |
Cytogenetics | 4q32.1 |
Summary | 'This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]' |
Protein Families | Druggable Genome |
Protein Pathways | Gap junction, Long-term depression, Purine metabolism, Vascular smooth muscle contraction |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400302 | GUCY1B3 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY400302 | Transient overexpression lysate of guanylate cyclase 1, soluble, beta 3 (GUCY1B3) |
USD 396.00 |
|
TP308205 | Recombinant protein of human guanylate cyclase 1, soluble, beta 3 (GUCY1B3) |
USD 823.00 |
{0} Product Review(s)
Be the first one to submit a review