Neurogenin3 (NEUROG3) (NM_020999) Human Mass Spec Standard

CAT#: PH324767

NEUROG3 MS Standard C13 and N15-labeled recombinant protein (NP_066279)

Product Images

Coomassie blue staining of purified NEUROG3 protein (Cat# TP324767). The protein was produced from HEK293T cells transfected with NEUROG3 cDNA clone (Cat# RC224767) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC224767
• Predicted MW: 22.9 kDa
• Protein Sequence:
  Sequence Link

  >RC224767 representing NM_020999
  Red=Cloning site Green=Tags(s)
  
  MTPQPSGAPTVQVTRETERSFPRASEDEVTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSR
  PKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLR
  IADHSLYALEPPAPHCGELGSPGGSPGDWGSLYSPVSQAGSLSPAASLEERPGLLGATSSACLSPGSLAF
  SDFL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: 50 ug/ml as determined by BCA
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_066279
• RefSeq Size: 1167
• RefSeq ORF: 642
• Synonyms: Atoh5; bHLHa7; Math4B; NGN-3; ngn3
• Locus ID: 50674
• UniProt ID: Q9Y4Z2
• Cytogenetics: 10q22.1
• Summary: The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4). [provided by RefSeq, May 2010]
• Protein Families: ES Cell Differentiation/IPS
• Protein Pathways: Maturity onset diabetes of the young