UNC5B (NM_170744) Human Recombinant Protein

CAT#: TP318267

Recombinant protein of human unc-5 homolog B (C. elegans) (UNC5B)

Product Images

Coomassie blue staining of purified UNC5B protein (Cat# TP318267). The protein was produced from HEK293T cells transfected with UNC5B cDNA clone (Cat# RC218267) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC218267. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 103.5 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_734465
• Locus ID: 219699
• UniProt ID: Q8IZJ1
• Cytogenetics: 10q22.1
• Refseq Size: 3935
• Refseq ORF: 2835
• Synonyms: p53RDL1; UNC5H2
• Summary: This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Axon guidance