ZIC2 (NM_007129) Human Recombinant Protein
CAT#: TP320798
Recombinant protein of human Zic family member 2 (odd-paired homolog, Drosophila) (ZIC2)
View other "ZIC2" proteins (3)
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
Recombinant protein was produced with TrueORF clone, RC220798. Click on the TrueORF clone link to view cDNA and protein sequences.
|
Tag | C-Myc/DDK |
Predicted MW | 54.8 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_009060 |
Locus ID | 7546 |
UniProt ID | O95409, A0A024RDY6 |
Cytogenetics | 13q32.3 |
Refseq Size | 2698 |
Refseq ORF | 1596 |
Synonyms | HPE5 |
Summary | This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. [provided by RefSeq, Jul 2016] |
Protein Families | Druggable Genome |
Protein Pathways | Hedgehog signaling pathway |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC416175 | ZIC2 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
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LY416175 | Transient overexpression lysate of Zic family member 2 (odd-paired homolog, Drosophila) (ZIC2) |
USD 605.00 |
|
PH320798 | ZIC2 MS Standard C13 and N15-labeled recombinant protein (NP_009060) |
USD 2,055.00 |
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