Rapsyn (RAPSN) (NM_005055) Human Recombinant Protein

CAT#: TP322710

Recombinant protein of human receptor-associated protein of the synapse (RAPSN), transcript variant 1

Product Images

Coomassie blue staining of purified RAPSN protein (Cat# TP322710). The protein was produced from HEK293T cells transfected with RAPSN cDNA clone (Cat# RC222710) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC222710. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 46.1 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_005046
• Locus ID: 5913
• UniProt ID: Q13702, A0A0S2Z4F8
• Cytogenetics: 11p11.2
• Refseq Size: 1664
• Refseq ORF: 1236
• Synonyms: CMS4C; CMS11; FADS; FADS2; RAPSYN; RNF205
• Summary: 'This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2011]'
• Protein Families: Druggable Genome