SCN4B (NM_174934) Human Recombinant Protein

CAT#: TP323951

Recombinant protein of human sodium channel, voltage-gated, type IV, beta (SCN4B), transcript variant 1

Product Images

Coomassie blue staining of purified SCN4B protein (Cat# TP323951). The protein was produced from HEK293T cells transfected with SCN4B cDNA clone (Cat# RC223951) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC223951. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 22 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_777594
• Locus ID: 6330
• UniProt ID: Q8IWT1, B0YJ93
• Cytogenetics: 11q23.3
• Refseq Size: 4489
• Refseq ORF: 684
• Synonyms: ATFB17; LQT10; Navbeta4
• Summary: 'The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.[provided by RefSeq, Mar 2009]'
• Protein Families: Ion Channels: Sodium, Transmembrane