Tgfbr1 (NM_009370) Mouse Recombinant Protein

CAT#: TP508091

Purified recombinant protein of Mouse transforming growth factor, beta receptor I (Tgfbr1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Specifications

Product Data

• Species: Mouse
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from Mouse cDNA ORF Clone, MR208091, encoding Mouse full-length Tgfbr1.
• Tag: C-MYC/DDK
• Predicted MW: 56.6 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_033396
• Locus ID: 21812
• UniProt ID: Q64729, Q4FJL1
• Cytogenetics: 4 26.02 cM
• Refseq Size: 5735
• Refseq ORF: 1509
• Synonyms: Alk-5; ALK5; AU017191; ESK2; TbetaR-I; TbetaRI; TGFR-1
• Summary: This gene encodes a member of the transforming growth factor beta (TGF-beta) receptor family of proteins. These proteins comprise one component of the TGF-beta signaling pathway, which transduces extracellular signals into gene expression changes to regulate a wide range of cellular responses, including proliferation, migration, differentiation and apoptosis. Homozygous knockout mice for this gene exhibit impaired angiogenesis and embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]