PROCR (NM_006404) Human Recombinant Protein
CAT#: TP720640XL
Purified recombinant protein of Human protein C receptor, endothelial (PROCR)
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Ser18-Ser210
|
Tag | C-His |
Predicted MW | 23.06 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_006395 |
Locus ID | 10544 |
UniProt ID | Q9UNN8 |
Cytogenetics | 20q11.22 |
Refseq Size | 1506 |
Refseq ORF | 714 |
Synonyms | CCCA; CCD41; EPCR |
Summary | The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013] |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
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