Semenogelin I (SEMG1) (NM_198139) Human Recombinant Protein
CAT#: TP720700XL
Purified recombinant protein of Human semenogelin I (SEMG1), transcript variant 2
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Gln24-Thr402
|
Tag | C-His |
Predicted MW | 43.8 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM Hac-NaAc, 150mM NaCl, pH 4.5. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_937782 |
Locus ID | 6406 |
UniProt ID | P04279 |
Cytogenetics | 20q13.12 |
Refseq Size | 1469 |
Refseq ORF | 1206 |
Synonyms | CT103; MGC14719; RATSVPIIA; semenogelin I; SEMG; seminal vesicle protein, secretion 2; seminal vesicle secretory protein 2; SGI; SVPIIA; Svs2; Svs2p2 |
Summary | The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. This preproprotein is proteolytically processed by the prostate-specific antigen (PSA) protease to generate multiple peptide products that exhibit distinct functions. One of these peptides, SgI-29, is an antimicrobial peptide with antibacterial activity. This proteolysis process also breaks down the gel matrix and allows the spermatozoa to move more freely. This gene and another similar semenogelin gene are present in a gene cluster on chromosome 20. [provided by RefSeq, Feb 2016] |
Protein Families | Secreted Protein |
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