Pancreatic Polypeptide (PPY) (NM_002722) Human Recombinant Protein

CAT#: TP762154

Purified recombinant protein of Human pancreatic polypeptide (PPY),Ala30-Arg88, N-terminal His-PDCD1(Pro21-Val170) tag, expressed in E. coli, 50ug


  View other "PPY" proteins (3)

USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Ala30-Arg88) of PPY
Tag N-terminal His-PDCD1(Pro21-Val170) tag
Predicted MW 23.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_002713
Locus ID 5539
UniProt ID P01298
Cytogenetics 17q21.31
Refseq Size 457
Refseq ORF 285
Synonyms PNP; PP
Summary 'This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]'
Protein Families Secreted Protein

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