Pancreatic Polypeptide (PPY) (NM_002722) Human Recombinant Protein
CAT#: TP762154
Purified recombinant protein of Human pancreatic polypeptide (PPY),Ala30-Arg88, N-terminal His-PDCD1(Pro21-Val170) tag, expressed in E. coli, 50ug
Other products for "PPY"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region(Ala30-Arg88) of PPY
|
Tag | N-terminal His-PDCD1(Pro21-Val170) tag |
Predicted MW | 23.5 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, 8M Urea, pH8.0 |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_002713 |
Locus ID | 5539 |
UniProt ID | P01298 |
Cytogenetics | 17q21.31 |
Refseq Size | 457 |
Refseq ORF | 285 |
Synonyms | PNP; PP |
Summary | 'This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]' |
Protein Families | Secreted Protein |
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