Human ALCAM ELISA Kit
USD 470.00
3 Weeks*
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Specifications
Product Data | |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Human ALCAM |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 312pg/ml-20,000pg/ml |
Sample Type | Cell culture supernates, serum and plasma(heparin , EDTA). |
Sample Volume | 100 ul |
Specificity | This kit is used for quantitative detection of human ALCAM |
Sensitivity | <10pg/ml |
Reactivities | Human |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins. In humans it is encoded by the ALCAM gene. The gene was mapped to human chromosome 3q13.1-q13.2 by fluorescence in situ hybridization of cDNA probes to metaphase chromosomes. It is also called CD166(cluster of differentiation 166), MEMD, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. It is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, neurons, melanoma cells, and also in sweat and sebaceous glands. CD166 protein expression is reported to be upregulated in a cell line deriving from a metastasizing melanoma. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development. Recently, CD166 has also been used as a potential cancer stem cell marker. |
Gene Symbol | ALCAM |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.