Bmp10 (NM_009756) Mouse Untagged Clone

CAT#: MC208193

Bmp10 (untagged) - Mouse bone morphogenetic protein 10 (Bmp10), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Bmp10
• Synonyms: b2b2711Clo
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC208193 representing NM_009756
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGGTCTCTGGTTCTGCCGCTGAGCGCCGTCTTCTGCCTGGTGGCTCACTCGGCTTCTGGCAGCCCCA
  TTATGGGCCTTGAGCAGTCGCCCCTGGAAGAAGACATGCCCTTCTTTGATGATATCTTCACGGAGCAAGA
  TGGTATTGACTTCAACACACTGCTGCAGAGCATGAAGAACGAGTTTCTCAAGACGCTGAACTTGTCGGAC
  ATTCCTGTGCAGGACACGGGCAGAGTGGATCCACCAGAGTACATGCTGGAGCTCTACAACAAATTCGCCA
  CAGACCGGACCTCCATGCCGTCTGCTAACATCATCCGGAGCTTCAAGAACGAAGATCTGTTTTCTCAACC
  AGTCACTTTTAATGGGCTCCGGAAATATCCTCTCCTCTTCAATGTGTCTATCCCTCACCATGAAGAGGTC
  GTCATGGCTGAACTGCGGTTGTACACGCTGGTGCAGAGAGATCGCATGATGTATGATGGCGTGGACCGTA
  AAATTACCATTTTTGAGGTACTAGAGAGTGCAGACGGTAGCGAGGAGGAGAGGAGCATGCTGGTCTTAGT
  ATCAACAGAGATCTACGGAACCAACAGTGAGTGGGAGACATTTGACGTCACAGATGCCACCAGACGTTGG
  CAAAAGTCAGGCCCATCAACCCATCAGCTGGAGATCCACATAGAAAGCAGACAAAACCAAGCTGAGGACA
  CCGGAAGGGGACAACTGGAAATAGATATGAGTGCCCAAAATAAGCATGACCCTTTGCTGGTTGTGTTTTC
  TGATGACCAAAGCAATGACAAGGAGCAGAAAGAAGAACTGAACGAATTGATCACCCATGAGCAGGATCTG
  GACCTGGACTCAGATGCTTTCTTCAGTGGGCCCGATGAAGAGGCTCTGCTGCAGATGAGGTCGAACATGA
  TTGATGATTCGTCCGCTCGGATCAGGAGGAACGCCAAGGGGAACTACTGTAAGAAGACCCCACTATACAT
  CGACTTCAAGGAGATTGGGTGGGACTCCTGGATCATCGCTCCTCCTGGGTATGAAGCCTATGAGTGCCGG
  GGTGTGTGTAACTACCCTCTGGCGGAGCACCTCACACCTACAAAACACGCAATTATTCAGGCCTTGGTCC
  ACCTCAAGAATTCCCAGAAAGCTTCCAAAGCCTGCTGTGTGCCCACGAAGCTGGATCCCATCTCCATCCT
  CTATTTAGATAAAGGTGTCGTCACCTACAAGTTTAAATATGAAGGGATGGCTGTGTCTGAGTGTGGCTGT
  AGATAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_009756
• ORF Size: 1266 bp
• Insert Size: 1266
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: BC145983, AAI45984
• RefSeq Size: 1317
• RefSeq ORF: 1266
• Locus ID: 12154
• Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation. Homozygous knockout mice for this gene exhibit impaired heart development and embryonic lethality. [provided by RefSeq, Aug 2016]