Mknk2 (NM_021462) Mouse Untagged Clone

CAT#: MC208964

Mknk2 (untagged) - Mouse MAP kinase-interacting serine/threonine kinase 2 (Mknk2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Mknk2
• Synonyms: 2010016G11Rik; Gprk7; Mnk2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC208964 representing NM_021462
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGTGCAGAAGAGAACAGCCGAACTTCAGGGCTTCCACCGTTCGTTCAAGGGGCAGAATCCTTTCGAGT
  TGGCCTTCTCCTTAGACCTCGCCCAGCACAGGGACTCTGACTTCAGCCCACAGTGTGAAGCCCGACCTGA
  CATGCCTTCCAGCCAGCCCATTGACATCCCAGATGCCAAGAAGAGAGGCCGGAAAAAGAAGCGCTGTCGG
  GCTACTGACAGCTTCTCAGGCAGGTTCGAAGATGTCTATCAGCTGCAGGAGGATGTGCTGGGGGAAGGTG
  CTCACGCTCGTGTGCAGACCTGTGTCAATCTCATCACCAACCAGGAATATGCTGTCAAGATCATTGAGAA
  GCAGCTGGGCCACATCCGCAGCAGGGTGTTCCGGGAGGTGGAGATGCTGTACCAGTGCCAGGGACATAGG
  AATGTTCTAGAACTGATTGAGTTCTTTGAGGAGGAGGACCGTTTCTACCTGGTGTTTGAGAAGATGCGTG
  GCGGATCCATCCTAAGCCACATCCATAGAAGGCGCCACTTTAACGAGCTGGAGGCCAGCGTGGTAGTACA
  GGACGTGGCCAGTGCCCTGGACTTCCTGCATAACAAAGGCATCGCCCACAGGGACCTAAAGCCAGAGAAC
  ATCCTATGTGAGCACCCCAACCAGGTCTCGCCAGTGAAGATCTGCGACTTCGACCTTGGCAGTGGTATCA
  AACTCAATGGAGACTGCTCCCCCATCTCCACACCAGAGCTGCTCACCCCGTGTGGGTCAGCTGAGTACAT
  GGCCCCAGAGGTGGTGGAGGCCTTCAGTGAAGAGGCCAGCATCTACGACAAGCGCTGCGACCTGTGGAGC
  CTGGGCGTCATCCTCTACATCCTGCTTAGTGGCTACCCGCCCTTCGTGGGCCACTGTGGCAGCGACTGTG
  GCTGGGACCGTGGGGAGGCCTGTCCTGCCTGCCAGAACATGCTGTTTGAGAGCATCCAGGAGGGCAAGTA
  TGAGTTCCCTGACAAGGACTGGTCCCACATCTCCTTTGCTGCCAAAGACCTCATCTCCAAGCTGCTGGTC
  CGAGATGCCAAGCAGAGGCTGAGTGCTGCCCAAGTCCTGCAGCATCCCTGGGTGCAGGGGTGTGCCCCAG
  AGAACACCCTACCGACACCCTTGGTTCTGCAGAGGAACAGCTGTGCCAAAGACCTCACGTCCTTTGCGGC
  TGAGGCCATCGCCATGAACCGGCAGCTGGCCCAGTGTGAGGAGGACGCTGGGCAGGACCAGCCTGTGGTC
  ATCCGAGCTACCTCACGCTGCCTGCAGCTGTCCCCACCCTCCCAGTCCAAGCTGGCCCAGCGGCGCCAGA
  GGGCTAGCCTGTCGGCCACCCCTGTGGTCCTTGTGGGGGATCGCGCATGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_021462
• ORF Size: 1380 bp
• Insert Size: 1380
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_021462.4, NP_067437.2
• RefSeq Size: 3448
• RefSeq ORF: 1380
• Locus ID: 17347
• Gene Summary: The protein encoded by this gene is a serine/threonine-protein kinase, which is targeted by both the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways. This enzyme targets several substrates including eukaryotic translation initiation factor 4E and mammalian target of rapamycin, which are negatively regulated by its phosphorylation. Null mutant mice do not exhibit developmental or reproductive defects. However, mice null for both this protein and mitogen-activated protein kinase-interacting serine/threonine protein kinase 1 have delayed tumor development in phosphatase and tensin homolog mutant mice, indicating an oncogenic function for this gene in tumor development. [provided by RefSeq, Oct 2014]