Rp1 (NM_001195662) Mouse Untagged Clone
CAT#: MC209321
Rp1 (untagged) - Mouse retinitis pigmentosa 1 (human) (Rp1), transcript variant 2, (10ug)
"NM_001195662" in other vectors (4)
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Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Symbol | Rp1 |
Synonyms | Dcdc3; Gm38717; mG145; Orp1; Rp1h |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC209321 representing NM_001195662
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCTTGAGAAATTGCAGGTCTCACCCAAAATGAGTGACACACCTTCTACTAGTTTCTCCATGATTCATC TGACTTCTGAAGGTCAAGTTCCTTCCCCTCGCCATTCAAATATCACTCATCCTGTAGTGGCTAAACGCAT CAGTTTCTATAAGAGTGGAGACCCACAGTTTGGCGGCGTTCGGGTGGTGGTCAACCCTCGTTCCTTTAAG ACTTTTGACGCTCTGCTGGACAGTTTATCCAGGAAGGTACCCCTGCCCTTTGGGGTAAGGAACATCAGCA CGCCCCGTGGACGACACAGCATCACCAGGCTGGAGGAGCTAGAGGACGGCAAGTCTTATGTGTGCTCCCA CAATAAGAAGGTGCTGCCAGTTGACCTGGACAAGGCCCGCAGGCGCCCTCGGCCCTGGCTGAGTAGTCGC TCCATAAGCACGCATGTGCAGCTCTGTCCTGCAACTGCCAATATGTCCACCATGGCACCTGGCATGCTCC GTGCCCCAAGGAGGCTCGTGGTCTTCCGGAATGGTGACCCGAAGAATAAGCATGTGGTCCTTCTTAGCCG GAGGATCACTCAGAGCTTCGAAGCCTTTCTGCAGTACCTGACACAGGTTATGCAGTGTCCTGTGGCCAAG CTGTATGCCACAGATGGAAGAAAAGTTCCTAGTCTCCAGGCAGTGATACTCAGCTCTGGAGCTGTGGTGG CAGCTGGAAGGGAGCCATTTAAACCAGGAAATTACGACATACAAAAGTACTTGCTTCCTGCCAAGTTACC AGGAATCTCTCATCGTGTGCACCAGAAGGGAAAAGCCAAGATAGAAAAAAGAAAGAATTATGGTTGGGGA CATAGGAACGCCGTTTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001195662 |
ORF Size | 858 bp |
Insert Size | 858 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Reference Data | |
RefSeq | NM_001195662.1, NP_001182591.1 |
RefSeq Size | 3047 |
RefSeq ORF | 858 |
Locus ID | 19888 |
Gene Summary | This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains, which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels, this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa. [provided by RefSeq, Jun 2019] Transcript Variant: This variant (2) has an alternate 5' exon, which results in an upstream in-frame AUG start codon, and an alternate 3' exon, as compared to variant 1. The resulting isoform (2) has a longer N-terminus, but has a much shorter and distinct C-terminus, as compared to isoform 1. The isoform 2 retains two doublecortin domains. |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MR226963 | Rp1 (Myc-DDK-tagged) - Mouse retinitis pigmentosa 1 (human) (Rp1), transcript variant 2 |
USD 68.00 |
|
MG226963 | Rp1 (GFP-tagged) - Mouse retinitis pigmentosa 1 (human) (Rp1) transcript variant 2, (10ug) |
USD 300.00 |
|
MR226963L3 | Lenti ORF clone of Rp1 (Myc-DDK-tagged) - Mouse retinitis pigmentosa 1 (human) (Rp1), transcript variant 2 |
USD 624.00 |
|
MR226963L4 | Lenti ORF clone of Rp1 (mGFP-tagged) - Mouse retinitis pigmentosa 1 (human) (Rp1), transcript variant 2 |
USD 500.00 |
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