Dclk1 (NM_001111051) Mouse Untagged Clone
CAT#: MC215711
Dclk1 (untagged) - Mouse doublecortin-like kinase 1 (Dclk1), transcript variant 2, (10ug)
"NM_001111051" in other vectors (4)
Product Images
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Symbol | Dclk1 |
Synonyms | 1700113D08Rik; 2810480F11Rik; AI836758; Click-I; Cpg16; Dcamkl1; Dcl; Dclk; mKIAA0369 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC215711 representing NM_001111051
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTTAGAGCTCATAGAAGTTAATGGAACCCCTGGTAGTCAGCTCTCTACTCCACGCTCGGGCAAGTCAC CAAGTCCATCACCCACCAGCCCAGGAAGCCTGCGGAAGCAGAGGATCTCTCAGCATGGCGGCTCCTCGAC TTCACTTTCATCCACTAAAGTTTGCAGCTCAATGGATGAGAATGATGGCCCTGGGGAAGAAGAGTCTGAG GAAGGCTTCCAGATTCCTGCCACAATAACAGAGAGATACAAAGTCGGGAGAACAATAGGAGACGGAAATT TTGCTGTTGTCAAGGAATGTATAGAGAGGTCGACTGCTCGGGAGTATGCCCTGAAAATCATCAAGAAAAG CAAATGCCGAGGCAAAGAGCACATGATCCAGAACGAGGTCTCCATCCTACGGAGGGTGAAGCACCCCAAC ATTGTCCTCCTGATTGAAGAGATGGATGTGCCGACTGAACTGTATCTTGTAATGGAATTAGTGAAGGGTG GAGACCTTTTCGATGCCATCACCTCCACTAGCAAATACACAGAGAGAGATGCCAGCGGGATGCTGTACAA CCTGGCCAGCGCCATCAAATACCTGCACAGCCTGAACATCGTCCACCGTGACATCAAGCCAGAGAATCTG CTGGTGTATGAGCACCAGGATGGCAGTAAGTCACTCAAGTTGGGTGACTTTGGCCTGGCCACAATTGTCG ACGGCCCCCTGTACACAGTCTGTGGCACCCCAACATATGTGGCTCCAGAAATCATTGCAGAGACTGGATA TGGCCTCAAGGTGGACATCTGGGCAGCTGGCGTGATCACTTATATCCTGCTGTGTGGCTTCCCTCCGTTC CGTGGAAGTGGGGATGACCAGGAGGTGCTTTTTGACCAGATCTTGATGGGCCAAGTGGACTTTCCATCTC CGTATTGGGACAATGTGTCAGATTCTGCTAAGGAGCTCATCAACATGATGCTGTTGGTTAACGTGGACCA GAGATTTTCAGCCGTGCAGGTCCTTGAGCATCCCTGGGTTAATGATGATGGTCTCCCAGAAAATGAGCAT CAGCTGTCAGTAGCTGGCAAAATCAAGAAGCATTTCAACACAGGCCCCAAGCCGAGCAGCACTGCAGCAG GAGTTTCTGTAATAGCAACCACCGCTCTTGATAAGGAGAGGCAGGTTTTCCGACGAAGACGCAACCAGGA TGTGAGGAGCCGGTACAAGGCGCAGCCAGCTCCACCGGAATTGAACTCGGAATCGGAGGACTACTCCCCC AGCTCCTCTGAGACTGTTCGCTCCCCCAATTCGCCCTTTTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001111051 |
ORF Size | 1302 bp |
Insert Size | 1302 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Reference Data | |
RefSeq | NM_001111051.1, NP_001104521.1 |
RefSeq Size | 6956 |
RefSeq ORF | 1302 |
Locus ID | 13175 |
Gene Summary | This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been found, but the biological validity of some variants has not been determined. These variants encode different isoforms, which are differentially expressed and have different kinase activities. [provided by RefSeq, Sep 2010] Transcript Variant: This variant (2, also known as DCLK-short-A, DCK-beta2, KIAA0369-BL or cpg16 (candidate plasticity gene 16)] is produced from the 3' promoter. It lacks several 5' exons but has an alternate 5' exon, as compared to variant 5. The resulting isoform (2) has a shorter and different N-terminus, and lacks doublecortin domains, as compared to isoform 5. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MR226410 | Dclk1 (Myc-DDK-tagged) - Mouse doublecortin-like kinase 1 (Dclk1), transcript variant 2 |
USD 450.00 |
|
MG226410 | Dclk1 (GFP-tagged) - Mouse doublecortin-like kinase 1 (Dclk1) transcript variant 2, (10ug) |
USD 500.00 |
|
MR226410L3 | Lenti ORF clone of Dclk1 (Myc-DDK-tagged) - Mouse doublecortin-like kinase 1 (Dclk1), transcript variant 2 |
USD 650.00 |
|
MR226410L4 | Lenti ORF clone of Dclk1 (mGFP-tagged) - Mouse doublecortin-like kinase 1 (Dclk1), transcript variant 2 |
USD 650.00 |
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